<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://www.w3.org/2000/01/rdf-schema#comment>	"A doen\u00E7a renal polic\u00EDstica (DRP), tamb\u00E9m conhecida como s\u00EDndrome renal polic\u00EDstica \u00E9 uma doen\u00E7a gen\u00E9tica que afeta os rins e tem car\u00E1ter progressivo. Ocorre em seres humanos e em alguns outros animais. A DRP \u00E9 caracterizada pela presen\u00E7a de v\u00E1rios cistos (da\u00ED o termo \"polic\u00EDstico\") em ambos os rins. A doen\u00E7a tamb\u00E9m pode acometer o f\u00EDgado, o p\u00E2ncreas, e mais raramente o cora\u00E7\u00E3o e o c\u00E9rebro. As duas principais formas de doen\u00E7a renal polic\u00EDstica s\u00E3o distinguidas por seus padr\u00F5es de heran\u00E7a gen\u00E9tica, dominante ou recessiva."@pt .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://www.w3.org/2000/01/rdf-schema#comment>	"La poliquistosis renal \u00E9s un trastorn gen\u00E8tic (hereditari) en qu\u00E8 es formen molts quists en els ronyons. Els quists formats en aquesta malaltia poden reempla\u00E7ar lentament gran part de la massa del teixit dels ronyons cosa que redueix la funci\u00F3 renal i condueix a insufici\u00E8ncia renal. Alguns problemes dels ronyons poden presentar-se quan el nen est\u00E0 encara en el ventre de la mare. Els signes de malaltia dels ronyons dels nens varien. Un nen pot tenir un creixement anormalment lent, vomitar sovint o tenir dolor d'esquena o de costat. Algunes malalties dels ronyons poden ser silencioses durant mesos o fins i tot anys. A vegades se l'anomena poliquistosis renal adulta, ja que sovint no es detecta fins aquesta etapa."@ca .
<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Wielotorbielowato\u015B\u0107 nerek, wielotorbielowate zwyrodnienie nerek (\u0142ac. degeneratio polycystica renum), PKD (od ang. polycystic kidney disease) \u2013 uwarunkowane genetycznie wyst\u0119powanie torbieli kory i rdzenia nerki. Dwa g\u0142\u00F3wne typy wielotorbielowato\u015Bci nerek s\u0105 klasyfikowane wed\u0142ug ich wzor\u00F3w dziedziczenia. Wyr\u00F3\u017Cnia si\u0119 wielotorbielowato\u015B\u0107 nerek dziedziczon\u0105 autosomalnie dominuj\u0105co (ang. autosomal dominant polycystic kidney disease, ADPKD) i posta\u0107 autosomaln\u0105 recesywn\u0105 (ang. autosomal recessive polycystic kidney disease, ARPKD). Wyst\u0119puje u ludzi i innych organizm\u00F3w. Wielotorbielowato\u015B\u0107 nerek charakteryzuje si\u0119 obecno\u015Bci\u0105 licznych torbieli w obu nerkach. Choroba zajmuje r\u00F3wnie\u017C w\u0105trob\u0119, trzustk\u0119, rzadko serce i m\u00F3zg."@pl .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://dbpedia.org/ontology/abstract>	"Zystennieren, auch als polyzystische Nieren bezeichnet, (englisch polycystic kidney disease, PKD) sind eine Gruppe ernsthafter, meist erblich bedingter Erkrankungen der Nieren. Durch die Bildung einer Vielzahl (altgriechisch \u03C0\u03BF\u03BB\u03CD\u03C2 polys \u201Aviel\u2018) von fl\u00FCssigkeitsgef\u00FCllten Kammern beziehungsweise Bl\u00E4schen, den sogenannten Zysten, sind die Nieren in ihrer Filterfunktion erheblich eingeschr\u00E4nkt. Bei einer Nierenzyste handelt es sich demgegen\u00FCber um eine einzelne Zyste, die im Rahmen einer Untersuchung als in aller Regel harmloser Zufallsbefund erw\u00E4hnt wird. Genetisch bedingte Zystennieren sind die h\u00E4ufigste lebensbedrohliche Erbkrankheit beim Menschen und eine der Hauptursachen f\u00FCr chronisches Nierenversagen. Eine Heilung ist nur durch eine Nierentransplantation m\u00F6glich."@de .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://dbpedia.org/ontology/abstract>	"\u591A\u767A\u6027\u56A2\u80DE\u814E(PKD) : \u67D3\u8272\u4F53\u512A\u6027\u591A\u767A\u6027\u56A2\u80DE\u814E\uFF08ADPKD\uFF09\uFF08\u305F\u306F\u3064\u305B\u3044\u306E\u3046\u307B\u3046\u3058\u3093\u3001\u82F1: Polycystic kidney disease : PKD\uFF09\u3001(\u305B\u3093\u3057\u3087\u304F\u305F\u3044\u3086\u3046\u305B\u3044\u305F\u306F\u3064\u305B\u3044\u306E\u3046\u307B\u3046\u3058\u3093\u3001\u82F1: Polycystic kidney diseaseAutosomal Dominant Polycystic Kidney Disease\uFF1AADPKD)\u306F\u3001\u4E21\u5074\u306E\u814E\u81D3\u306B\u591A\u767A\u6027\u306E\u56A2\u80DE\u304C\u751F\u3058\u3066\u6162\u6027\u814E\u4E0D\u5168\u3092\u751F\u3058\u308B\u907A\u4F1D\u6027\u75BE\u60A3\u3002 \u4E21\u65B9\u306E\u814E\u81D3\u306B\u3067\u304D\u305F\u591A\u767A\u6027\u306E\u56A2\u80DE\u304C\u5F90\u3005\u306B\u5927\u304D\u304F\u306A\u308A\u9032\u884C\u6027\u306B\u814E\u6A5F\u80FD\u304C\u4F4E\u4E0B\u3059\u308B\u6700\u3082\u983B\u5EA6\u306E\u9AD8\u3044\u907A\u4F1D\u6027\u814E\u75BE\u60A3\u3002 \n* \u5C3F\u7D30\u7BA1\u306E\u592A\u3055\u3092\u8ABF\u7BC0\u3059\u308BPKD\u907A\u4F1D\u5B50\u306E\u7570\u5E38\u304C\u539F\u56E0\u3002\u591A\u304F\u306F\u6210\u4EBA\u306B\u306A\u3063\u3066\u304B\u3089\u767A\u75C7\u305770\u6B73\u307E\u3067\u306B\u7D04\u534A\u6570\u304C\u900F\u6790\u5C0E\u5165\u3002\u75C7\u72B6\u306F\u9AD8\u8840\u5727\u3001\u809D\u56A2\u80DE\u3001\u8133\u52D5\u8108\u7624\u3001\u81B5\u81D3\u3001\u813E\u81D3\u3001\u5C3F\u8DEF\u611F\u67D3\u75C7\u3001\u304F\u3082\u819C\u3001\u50E7\u5E3D\u5F01\u9038\u8131\u75C7\u3001\u5927\u8178\u61A9\u5BA4\u3001\u9F20\u5F84\u30D8\u30EB\u30CB\u30A2\u3001\u305D\u306E\u4ED6\u3000"@ja .
<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://dbpedia.org/ontology/abstract>	"\u041F\u043E\u043B\u0438\u043A\u0438\u0441\u0442\u043E\u0301\u0437 \u043F\u043E\u0447\u0435\u043A (\u0441\u0438\u043D\u043E\u043D\u0438\u043C: \u043F\u043E\u043B\u0438\u043A\u0438\u0441\u0442\u043E\u0437\u043D\u0430\u044F \u0431\u043E\u043B\u0435\u0437\u043D\u044C \u043F\u043E\u0447\u0435\u043A, \u0441\u043E\u043A\u0440. \u041F\u0411\u041F) \u043F\u0440\u0435\u0434\u0441\u0442\u0430\u0432\u043B\u044F\u0435\u0442 \u0441\u043E\u0431\u043E\u0439 \u0433\u0435\u043D\u0435\u0442\u0438\u0447\u0435\u0441\u043A\u043E\u0435 \u0437\u0430\u0431\u043E\u043B\u0435\u0432\u0430\u043D\u0438\u0435, \u043F\u0440\u043E\u044F\u0432\u043B\u044F\u044E\u0449\u0435\u0435\u0441\u044F \u043A\u0438\u0441\u0442\u043E\u0437\u043D\u044B\u043C \u043F\u0435\u0440\u0435\u0440\u043E\u0436\u0434\u0435\u043D\u0438\u0435\u043C \u043F\u0430\u0440\u0435\u043D\u0445\u0438\u043C\u044B \u043F\u043E\u0447\u0435\u043A. \u041E\u0434\u043D\u0430 \u0438\u0437 \u0444\u043E\u0440\u043C . \u0411\u043E\u043B\u0435\u0437\u043D\u044C \u0437\u0430\u0442\u0440\u0430\u0433\u0438\u0432\u0430\u0435\u0442 \u043D\u0435 \u0442\u043E\u043B\u044C\u043A\u043E \u0441\u0430\u043C\u0438 \u043F\u043E\u0447\u043A\u0438, \u043D\u043E \u0447\u0430\u0441\u0442\u043E \u0442\u0430\u043A\u0436\u0435 \u0434\u0440\u0443\u0433\u0438\u0435 \u043E\u0440\u0433\u0430\u043D\u044B (\u043F\u0435\u0447\u0435\u043D\u044C)."@ru .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://dbpedia.org/ontology/abstract>	"La malattia policistica renale, meglio nota come rene policistico o anche policistosi renale, \u00E8 una malattia genetica di tipo cistico. Ne esistono due forme: una autosomica dominante, pi\u00F9 comune e tipica dell'adulto, e una autosomica recessiva, pi\u00F9 rara e presente nell'infanzia. La forma autosomica dominante \u00E8 causata da mutazioni genetiche del gene nell'85% dei casi e di nel 10-15% dei casi; molto pi\u00F9 rare sono invece la forma autosomica recessiva e la nefronoftisi, responsabili di un maggiore tasso di mortalit\u00E0. Entrambe le forme possono condurre a insufficienza renale cronica."@it .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://www.w3.org/2000/01/rdf-schema#comment>	"La malattia policistica renale, meglio nota come rene policistico o anche policistosi renale, \u00E8 una malattia genetica di tipo cistico. Ne esistono due forme: una autosomica dominante, pi\u00F9 comune e tipica dell'adulto, e una autosomica recessiva, pi\u00F9 rara e presente nell'infanzia. La forma autosomica dominante \u00E8 causata da mutazioni genetiche del gene nell'85% dei casi e di nel 10-15% dei casi; molto pi\u00F9 rare sono invece la forma autosomica recessiva e la nefronoftisi, responsabili di un maggiore tasso di mortalit\u00E0. Entrambe le forme possono condurre a insufficienza renale cronica."@it .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://dbpedia.org/ontology/abstract>	"Polycystic kidney disease (PKD or PCKD, also known as polycystic kidney syndrome) is a genetic disorder in which the renal tubules become structurally abnormal, resulting in the development and growth of multiple cysts within the kidney. These cysts may begin to develop in utero, in infancy, in childhood, or in adulthood. Cysts are non-functioning tubules filled with fluid pumped into them, which range in size from microscopic to enormous, crushing adjacent normal tubules and eventually rendering them non-functional as well. PKD is caused by abnormal genes that produce a specific abnormal protein; this protein has an adverse effect on tubule development. PKD is a general term for two types, each having their own pathology and genetic cause: autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD). The abnormal gene exists in all cells in the body; as a result, cysts may occur in the liver, seminal vesicles, and pancreas. This genetic defect can also cause aortic root aneurysms, and aneurysms in the circle of Willis cerebral arteries, which if they rupture, can cause a subarachnoid hemorrhage. Diagnosis may be suspected from one, some, or all of the following: new onset flank pain or red urine; a positive family history; palpation of enlarged kidneys on physical exam; an incidental finding on abdominal sonogram; or an incidental finding of abnormal kidney function on routine lab work (BUN, serum creatinine, or eGFR). Definitive diagnosis is made by abdominal CT exam. Complications include hypertension due to the activation of the renin\u2013angiotensin\u2013aldosterone system (RAAS), frequent cyst infections, urinary bleeding, and declining renal function. Hypertension is treated with angiotensin converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs). Infections are treated with antibiotics. Declining renal function is treated with renal replacement therapy (RRT): dialysis and/or transplantation. Management from the time of the suspected or definitive diagnosis is by a board-certified nephrologist."@en .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://dbpedia.org/ontology/abstract>	"Polycystisk njursjukdom \u00E4r \u00E4rftlig njursjukdom och finns i tv\u00E5 varianter. Vid den recessiva varianten d\u00F6r man under f\u00F6rsta levnads\u00E5ret p\u00E5 grund av njur- eller leversvikt. Adult polycystic kidney disease (APKD) \u00E4r en t\u00E4mligen vanlig sjukdom. Endast diabetes och h\u00F6gt blodtryck ansvarar f\u00F6r fler njurrelaterade skador \u00E4n APKD. APKD \u00E4rvs autosomalt dominant. Sm\u00E5 cystor finns i barndomen och de f\u00F6rstoras d\u00E5 patienten blir \u00E4ldre. I fullt utvecklad APKD \u00E4r njurarna bilateralt f\u00F6rstorade och kan v\u00E4ga uppemot 4,5kg styck. Den drabbade k\u00E4nner ofta inget f\u00F6rr\u00E4n senare i livet. I tjugo\u00E5rs\u00E5ldern kan h\u00F6gt blodtryck uppkomma. 30% av de med APKD har levercystor. Med APKD har man \u00F6kad risk f\u00F6r , hj\u00E4rnbl\u00F6dning och br\u00E5ck."@sv .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Polycystic kidney disease (PKD or PCKD, also known as polycystic kidney syndrome) is a genetic disorder in which the renal tubules become structurally abnormal, resulting in the development and growth of multiple cysts within the kidney. These cysts may begin to develop in utero, in infancy, in childhood, or in adulthood. Cysts are non-functioning tubules filled with fluid pumped into them, which range in size from microscopic to enormous, crushing adjacent normal tubules and eventually rendering them non-functional as well."@en .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Polycystic_liver_disease> .
<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Cystic_kidney_disease> .
<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Proteinuria> .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Nephrology> .
<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://www.w3.org/2000/01/rdf-schema#label>	"\u041F\u043E\u043B\u0456\u043A\u0456\u0441\u0442\u043E\u0437 \u043D\u0438\u0440\u043E\u043A"@uk .
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<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://dbpedia.org/ontology/abstract>	"La poliquistosis renal \u00E9s un trastorn gen\u00E8tic (hereditari) en qu\u00E8 es formen molts quists en els ronyons. Els quists formats en aquesta malaltia poden reempla\u00E7ar lentament gran part de la massa del teixit dels ronyons cosa que redueix la funci\u00F3 renal i condueix a insufici\u00E8ncia renal. Alguns problemes dels ronyons poden presentar-se quan el nen est\u00E0 encara en el ventre de la mare. Els signes de malaltia dels ronyons dels nens varien. Un nen pot tenir un creixement anormalment lent, vomitar sovint o tenir dolor d'esquena o de costat. Algunes malalties dels ronyons poden ser silencioses durant mesos o fins i tot anys. A vegades se l'anomena poliquistosis renal adulta, ja que sovint no es detecta fins aquesta etapa. Aquesta malaltia \u00E9s la quarta causa d'insufici\u00E8ncies renals al m\u00F3n, i actualment la pateixen unes 12,5 milions de persones."@ca .
<http://dbpedia.org/resource/Polycystic_kidney_disease>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Cerebral_arteries> .
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