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Subject Item
dbr:Omega_hydroxy_acid
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yago:Substance100019613 yago:WikicatHydroxyAcids yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Matter100020827 yago:Material114580897 yago:Relation100031921 yago:Part113809207 dbr:Class yago:PhysicalEntity100001930 yago:Acid114607521 yago:HydroxyAcid114613922
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Omega hydroxy acid Ω-羟基酸
rdfs:comment
Omega hydroxy acids (also known as ω-hydroxy acids) are a class of naturally occurring straight-chain aliphatic organic acids n carbon atoms long with a carboxyl group at position 1 (the starting point for the family of carboxylic acids), and a hydroxyl at terminal position n where n > 3. The C16 and C18 omega hydroxy acids 16-hydroxy palmitic acid and 18-hydroxy stearic acid are key monomers of cutin in the plant cuticle. The polymer cutin is formed by inter-esterification of omega hydroxy acids and derivatives of them that are substituted in mid-chain, such as 10,16-dihydroxy palmitic acid. Only the epidermal cells of plants synthesize cutin. Ω-羟基酸(英語:Ω-Hydroxy acids 或 Omega hydroxy acid)是羧酸的末端碳原子上的氢被羟基取代的产物,通常碳链长度大于3,常见于植物的角質。
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dbr:Shiina_macrolactonization dbr:Heptatriacontanoic_acid dbr:Cutin dbr:Carboxylic_acid dbr:Polyester dbr:2-Methyl-6-nitrobenzoic_anhydride n23:this dbr:Hydroxy_acid dbr:Beta_hydroxy_acid dbr:Juniperic_acid dbr:Ω-hydroxy_acid wikipedia-en:Omega_hydroxy_acid dbr:Alpha_hydroxy_acid dbr:Plant_cuticle
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dbr:Gamma-Hydroxybutyric_acid dbr:Carboxyl dbr:Beta_hydroxy_acid dbr:Ozone dbc:Hydroxy_acids dbr:Stearic_acid dbr:Hydroxyl dbr:CYP4F2 dbr:Microsome dbr:Palmitic_acid dbr:Alpha_hydroxy_acid dbr:CYP4A22 dbr:CYP4A11 dbr:Pinus_radiata dbr:Arachidonic_acid dbr:Plant_cuticle dbr:Esterification dbr:3-Hydroxypropionic_acid dbr:Carbonic_acid dbr:Carboxylic_acid dbc:Plant_physiology dbr:Angelica_archangelica dbr:Cutin dbr:5-Hydroxypentanoic_acid dbr:Sabinic_acid dbr:Hydroxy_acid dbr:Polymer dbr:Glycolic_acid dbr:Leukotriene_B4 dbr:Juniperic_acid dbr:5-Hydroxyicosatetraenoic_acid dbr:20-Hydroxyeicosatetraenoic_acid dbr:Cytochrome_P450 dbr:Aliphatic dbr:CYP4F3
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dbo:abstract
Ω-羟基酸(英語:Ω-Hydroxy acids 或 Omega hydroxy acid)是羧酸的末端碳原子上的氢被羟基取代的产物,通常碳链长度大于3,常见于植物的角質。 Omega hydroxy acids (also known as ω-hydroxy acids) are a class of naturally occurring straight-chain aliphatic organic acids n carbon atoms long with a carboxyl group at position 1 (the starting point for the family of carboxylic acids), and a hydroxyl at terminal position n where n > 3. The C16 and C18 omega hydroxy acids 16-hydroxy palmitic acid and 18-hydroxy stearic acid are key monomers of cutin in the plant cuticle. The polymer cutin is formed by inter-esterification of omega hydroxy acids and derivatives of them that are substituted in mid-chain, such as 10,16-dihydroxy palmitic acid. Only the epidermal cells of plants synthesize cutin. Omega hydroxy fatty acids also occur in animals. Cytochrome P450 (CYP450) microsome ω-hydroxylases such as CYP4A11, CYP4A22, CYP4F2, and CYP4F3 in humans, Cyp4a10 and Cyp4a12 in mice, and Cyp4a1, Cyp4a2, Cyp4a3, and Cyp4a8 in rats metabolize arachidonic acid and many arachidonic acid metabolites to their corresponding omega hydroxyl products. This metabolism of arachidonic acid produces 20-hydroxyarachidonic acid (i.e. 20-hydroxyeicosatetraeonic acid or 20-HETE), a bioactive product involved in various physiological and pathological processes; and this metabolism of certain bioactive arachidonic acid metabolites such as leukotriene B4, 5-hydroxyicosatetraenoic acid, and 5-hydroxyicosatetraenoic acid produces 20-hydroxylated products which are 100- to 1,000-fold weaker than, and therefore represents the inactivation of, their respective precursors.
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