About: A physiological approach to understand the role of respiratory effort in the progression of lung injury in SARS-CoV-2 infection

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About: A physiological approach to understand the role of respiratory effort in the progression of lung injury in SARS-CoV-2 infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A physiological approach to understand the role of respiratory effort in the progression of lung injury in SARS-CoV-2 infection
Creator	Cruces, Pablo Díaz, Franco Erranz, Benjamín González, Carlos Hurtado, Daniel Iturrieta, Pablo Retamal, Jaime
Source	Medline; PMC
abstract	Deterioration of lung function during the first week of COVID-19 has been observed when patients remain with insufficient respiratory support. Patient self-inflicted lung injury (P-SILI) is theorized as the responsible, but there is not robust experimental and clinical data to support it. Given the limited understanding of P-SILI, we describe the physiological basis of P-SILI and we show experimental data to comprehend the role of regional strain and heterogeneity in lung injury due to increased work of breathing. In addition, we discuss the current approach to respiratory support for COVID-19 under this point of view.
has issue date	2020-08-10(xsd:dateTime)
bibo:doi	10.1186/s13054-020-03197-7
bibo:pmid	32778136
has license	cc-by
sha1sum (hex)	10723f6163e4db193c344b331e39c8cddd0ba3f3
schema:url	https://doi.org/10.1186/s13054-020-03197-7
resource representing a document's title	A physiological approach to understand the role of respiratory effort in the progression of lung injury in SARS-CoV-2 infection
has PubMed Central identifier	PMC7416996
has PubMed identifier	32778136
schema:publication	Crit Care
resource representing a document's body	covid:10723f6163e4db193c344b331e39c8cddd0ba3f3#body_text
is schema:about of	named entity 'current' named entity 'lung injury' named entity 'COVID-19' named entity 'GIVEN' named entity 'LIMITED' named entity '28P' named entity 'DESCRIBE' named entity 'COMPREHEND' named entity 'TO SUPPORT' named entity 'breathing' named entity 'lung function' named entity 'respiratory support' named entity 'ligand' named entity 'lungs' named entity 'mammals' named entity 'mechanical ventilators' named entity 'dyspnea' named entity 'atelectasis' named entity 'ventilator' named entity 'histology' named entity 'histopathological' named entity 'hypoxemia' named entity 'perivascular' named entity 'non-invasive' named entity 'viscoelastic' named entity 'intubated' named entity 'mechanotransduction' named entity 'respiratory musculature' named entity 'phenotypes' named entity 'apoptosis' named entity 'dehydration' named entity 'HFNC' named entity 'respiratory rate' named entity 'respiratory support' named entity 'consciousness' named entity 'Inflammation' named entity 'transpulmonary pressure' named entity 'ARDS' named entity 'respiratory support' named entity 'intrathoracic pressure' named entity 'acidosis' named entity 'weaning' named entity 'NIV' named entity 'lungs' named entity 'respiratory failure' named entity 'hyperemia' named entity 'hemorrhage' named entity 'mechanical ventilation' named entity 'Tnfsf13b' named entity 'lung tissue' named entity 'thromboembolic events' named entity 'ARF' named entity 'volumetric strain' named entity 'COVID' named entity 'SARS-CoV2' named entity 'SARS-CoV2' named entity 'tidal volume' named entity 'mechanical ventilation' named entity 'ARDS' named entity 'lung function' named entity 'lung tissue' named entity 'WOB' named entity 'NIV' named entity 'non-invasive' named entity 'Intensive care units' named entity 'ARDS' named entity 'aerosolization' named entity 'NIV' named entity 'ventilator' named entity 'infection' named entity 'intubation' named entity 'Thermo Fisher Scientific' named entity 'FRC' named entity 'non-invasive' named entity 'ARDS'

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