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Afloqualone (Arofuto) is a quinazolinone family GABAergic drug and is an analogue of methaqualone developed in the 1970s by a team at Tanabe Seiyaku. It has sedative and muscle-relaxant effects resulting from its agonist activity at the β subtype of the GABAa receptor and has had some clinical use, although it causes photosensitization as a side-effect that can cause skin problems such as dermatitis.

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  • Afloqualone
  • アフロカロン
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  • アフロクアロン(Afloqualone)は、キナゾリノン系のGABA作動薬で、1970年代に田辺製薬が開発したのアナログである。β型のGABAA受容体のアゴニストとしての働きに由来する鎮静と筋弛緩剤作用がある。一部臨床用にも用いられているが、感光性のために、皮膚炎等の皮膚疾患が副作用として現れることがある。
  • Afloqualone (Arofuto) is a quinazolinone family GABAergic drug and is an analogue of methaqualone developed in the 1970s by a team at Tanabe Seiyaku. It has sedative and muscle-relaxant effects resulting from its agonist activity at the β subtype of the GABAa receptor and has had some clinical use, although it causes photosensitization as a side-effect that can cause skin problems such as dermatitis.
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  • D01638
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http://purl.org/li...ics/gold/hypernym
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  • アフロクアロン(Afloqualone)は、キナゾリノン系のGABA作動薬で、1970年代に田辺製薬が開発したのアナログである。β型のGABAA受容体のアゴニストとしての働きに由来する鎮静と筋弛緩剤作用がある。一部臨床用にも用いられているが、感光性のために、皮膚炎等の皮膚疾患が副作用として現れることがある。
  • Afloqualone (Arofuto) is a quinazolinone family GABAergic drug and is an analogue of methaqualone developed in the 1970s by a team at Tanabe Seiyaku. It has sedative and muscle-relaxant effects resulting from its agonist activity at the β subtype of the GABAa receptor and has had some clinical use, although it causes photosensitization as a side-effect that can cause skin problems such as dermatitis.
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  • Unscheduled
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