About: Cyclin-dependent kinase 4

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Cyclin-dependent kinase 4 also known as cell division protein kinase 4 is an enzyme that in humans is encoded by the CDK4 gene. CDK4 is a member of the cyclin-dependent kinase family.

Attributes	Values
type	Thing biomolecule Enzyme gene yago:Abstraction100002137 yago:PhysicalEntity100001930 yago:Part113809207 yago:Relation100031921 Biomolecule protein HumanGene dbo:Gene yago:Chemical114806838 yago:Compound114818238 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Protein114728724 yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatProteins
label	Cdk4 Cyclin-dependent kinase 4 CDK4 Циклін-залежна кіназа 4 サイクリン依存性キナーゼ4 周期蛋白依赖性激酶4
comment	La quinasa dependiente de ciclina 4 también conocida como Cdk4, es una enzima que en los humanos es codificado por el gen CDK4. Como su nombre lo indica, la Cdk4 es miembro de la familia de quinasas dependientes de ciclinas y miembro de la familia de las serina/treonina proteína kinasas, que presenta un alto grado de homología con Cdc28 sintetizada por la especie S. cerevisiae y cdc2 de la especie S. pombe. La CDK4 est une kinase dépendante des cyclines. Son gène est le CDK4 situé sur le chromosome 12 humain. サイクリン依存性キナーゼ4（サイクリンいぞんせいキナーゼ4、英: Cyclin-dependent kinase 4、略称: CDK4）は、ヒトではCDK4遺伝子にコードされる酵素である。CDK4はサイクリン依存性キナーゼ（CDK）ファミリーに属する。周期蛋白依赖性激酶4（英語：cyclin-dependent kinases 4，CDK4）是周期蛋白依赖性激酶家族成員之一，是真核細胞中調控細胞週期的蛋白質。 CDK4 (англ. Cyclin dependent kinase 4) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 12-ї хромосоми. Довжина поліпептидного ланцюга білка становить 303 амінокислот, а молекулярна маса — 33 730. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Cyclin-dependent kinase 4 also known as cell division protein kinase 4 is an enzyme that in humans is encoded by the CDK4 gene. CDK4 is a member of the cyclin-dependent kinase family.
sameAs	Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4 Cyclin-dependent kinase 4
topic	Granulopoiesis Cyclin-dependent kinase 6 CEBPA CDKN2B dbr:Neochromosome cell cycle Sarcoma Cyclin Cyclin D3 P21 CDKN2A Restriction point dbr:CDC37 dbr:MyoD dbr:List_of_MeSH_codes_(D08) dbr:List_of_MeSH_codes_(D12.644) dbr:List_of_MeSH_codes_(D12.776) dbr:List_of_MeSH_codes_(D12.776.476) Cyclin D1 Proliferating cell nuclear antigen CDKN1B P16 dbr:Abemaciclib dbr:Cyclin-dependent_kinase_inhibitor_protein dbr:Cyclin_D Cellular senescence dbr:Cdk4 dbr:Drebrin-like dbr:Drug_nomenclature dbr:SERTAD1 dbr:Astex_Pharmaceuticals dbr:CDK4 dbr:CDK4_(gene) dbr:CDK4_gene dbr:CDK4_inhibitor dbr:CDKN2C dbr:CIP/KIP dbr:CNKSR2 dbr:Cyclin-CDK4 dbr:Cyclin_D2 dbr:G1/S_transition wikipedia-en:Cyclin-dependent_kinase_4 dbr:Cyclin-dependent_kinase_4#this
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described by	https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/class/yago/Compound114818238 proxy:entity/http/dbpedia.org/resource/Cell_cycle https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/Template:Infobox_gene https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/Gene https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/class/yago/OrganicCompound114727670

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