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Fibroblast growth factor 23 (FGF23) is a protein and member of the fibroblast growth factor (FGF) family which participates in the regulation of phosphate in plasma and vitamin D metabolism. In humans it is encoded by the FGF23 gene. FGF23 decreases reabsorption of phosphate in the kidney. Mutations in FGF23 can lead to its increased activity, resulting in autosomal dominant hypophosphatemic rickets.

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type
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  • Facteur 23 de croissance du fibroblaste
  • Factor de crecimiento fibroblástico 23
  • Fibroblast growth factor 23
  • FGF23
  • FGF23
  • Fator de crescimento fibroblástico 23
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  • El Factor de crecimiento fibroblástico 23 (FGF23) es una proteína que en humanos es codificada por el gen FGF23. El FGF23 es miembro de la familia de factores de crecimiento fibroblástico, responsable del metabolismo del fósforo a nivel renal.
  • FGF23 est une protéine appartenant à la famille des facteurs de croissances des fibroblastes (« fibroblast growth factor 23 »). Son gène est FGF23 situé sur le chromosome 12 humain.
  • Il fattore di crescita dei fibroblasti 23 o FGF23 (dall'inglese Fibroblast Growth Factor 23) è una proteina che nell'uomo è codificata dal gene FGF23.L'FGF23 appartiene alla famiglia dei fattori di crescita dei fibroblasti, coinvolta nel metabolismo dei fosfati.
  • O fator de crescimento fibroblástico 23 ou FGF 23 (do inglês fibroblast growth factor 23), é um hormônio produzido pelo osso, mais especificamente pelas células do tecido ósseo chamadas osteoblastos e osteócitos. Tem como funções aumentar a excreção de fósforo pelos rins e inibir a forma ativa da vitamina D (calcitriol), protegendo contra o excesso de vitamina D e evitando a retenção de fósforo no organismo, conhecida como hiperfosfatemia.
  • FGF23 (англ. Fibroblast growth factor 23) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 12-ї хромосоми. Довжина поліпептидного ланцюга білка становить 251 амінокислот, а молекулярна маса — 27 954. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин
  • Fibroblast growth factor 23 (FGF23) is a protein and member of the fibroblast growth factor (FGF) family which participates in the regulation of phosphate in plasma and vitamin D metabolism. In humans it is encoded by the FGF23 gene. FGF23 decreases reabsorption of phosphate in the kidney. Mutations in FGF23 can lead to its increased activity, resulting in autosomal dominant hypophosphatemic rickets.
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