About: HBx   Goto Sponge  NotDistinct  Permalink

An Entity of Type : yago:WikicatViralProteins, within Data Space : wasabi.inria.fr associated with source document(s)

HBx is a hepatitis B viral protein. It is 154 amino acids long and interferes with transcription, signal transduction, cell cycle progress, protein degradation, apoptosis and chromosomal stability in the host. It forms a heterodimeric complex with its cellular target protein (HBX interacting protein: HBXIP), and this interaction dysregulates centrosome dynamics and mitotic spindle formation. It interacts with DDB1 (Damaged DNA Binding Protein 1) redirecting the ubiquitin ligase activity of the -DDB1 E3 complexes, which are intimately involved in the intracellular regulation of DNA replication and repair, transcription and signal transduction.

AttributesValues
type
label
  • HBx
  • HBx
comment
  • HBx adakah protein virus hepatitis B. Protein ini memiliki panjang 154 asam amino dan mengganggu transkripsi, transduksi sinyal, perkembangan siklus sel, degradasi protein, apoptosis, dan stabilitas kromosom pada sel inang. Protein ini membentuk kompleks heterodimer dengan protein target selulernya (protein yang berinteraksi dengan HBX: ), dan interaksi ini mendisregulasi dinamika sentrosom dan pembentukan pemintal kromosom. Protein ini berinteraksi dengan (Protein Pengikatan DNA Rusak 1), mengalihkan aktivitas dari kompleks -DDB1 yang secara detail melibatkan regulasi replikasi dan perbaikan DNA intraseluler, , dan transduksi sinyal.
  • HBx is a hepatitis B viral protein. It is 154 amino acids long and interferes with transcription, signal transduction, cell cycle progress, protein degradation, apoptosis and chromosomal stability in the host. It forms a heterodimeric complex with its cellular target protein (HBX interacting protein: HBXIP), and this interaction dysregulates centrosome dynamics and mitotic spindle formation. It interacts with DDB1 (Damaged DNA Binding Protein 1) redirecting the ubiquitin ligase activity of the -DDB1 E3 complexes, which are intimately involved in the intracellular regulation of DNA replication and repair, transcription and signal transduction.
sameAs
name
  • Protein X
  • Transactivation protein X
topic
depiction
  • External Image
described by
subject
dbo:wikiPageID
Wikipage revision ID
dbo:wikiPageWikiLink
Faceted Search & Find service v1.13.91 as of Mar 24 2020


Alternative Linked Data Documents: Sponger | ODE     Content Formats:       RDF       ODATA       Microdata      About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data]
OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software