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Interleukin 24 (IL-24) is a protein in the interleukin family, a type of cytokine signaling molecule in the immune system. In humans, this protein is encoded by the IL24 gene. IL-24 is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. IL-24 appears to control cell survival and proliferation by inducing rapid activation of particular transcription factors called STAT1 and STAT3. This cytokine is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells and acts on skin, lung, and reproductive tissues. IL-24 performs important roles in wound h

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  • Interleukin 24
  • Interleukine 24
  • IL24
  • Interleukin 24
  • Interleukina 24
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  • L'interleukine 24 (ou IL-24) est une cytokine sécrétée par les monocytes, les cellules endothéliales, les mélanocytes, les lymphocytes Th2 ainsi que les myofibroblastes subépithéliaux du côlon. L'expression de l'IL-24 est notamment induite par l'IL-1β, l'IL-17, l'IL-22 et le lipopolysaccharide bactérien. Elle codée par le gène IL24 situé sur le chromosome 1 humain . L'IL-24 a également la particularité d'être une cytokine à action pro-apoptotique.
  • Interleukina 24, IL-24 – jest to, podobnie jak interleukina 19, homolog interleukiny 10. Została zidentyfikowana początkowo jako produkt genu . Indukuje ona apoptozę komórek nowotworowych, wywodzących się z wielu narządów, takich jak np. czerniak oraz glejak.
  • Interleukin 24 (IL-24) je protein, který je u lidí kódován genem IL24. Gen pro IL-24 se u lidí nachází na chromozomu 1.
  • IL24 (англ. Interleukin 24) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 1-ї хромосоми. Довжина поліпептидного ланцюга білка становить 206 амінокислот, а молекулярна маса — 23 825. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин
  • Interleukin 24 (IL-24) is a protein in the interleukin family, a type of cytokine signaling molecule in the immune system. In humans, this protein is encoded by the IL24 gene. IL-24 is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. IL-24 appears to control cell survival and proliferation by inducing rapid activation of particular transcription factors called STAT1 and STAT3. This cytokine is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells and acts on skin, lung, and reproductive tissues. IL-24 performs important roles in wound h
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