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The Great Imitator (also the Great Masquerader) is a phrase used for medical conditions that feature nonspecific symptoms and may be confused with a number of other diseases. The term connotes especially difficult differential diagnosis (DDx), especial potential for misdiagnosis, and the protean nature of some diseases. Most great imitators are systemic in nature or have systemic sequelae, and an aspect of nonspecific symptoms is logically almost always involved. In some cases, an assumption that a particular sign or symptom, or a particular pattern of several thereof, is pathognomonic turns out to be false, as the reality is that it is only nearly so.

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  • The great imitator
  • مقلد عظيم (طب)
  • 偉大的模仿者
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  • المُقلد العظيم (بالإنجليزية: The great imitator)‏ أو المُتخفي العَظيم (بالإنجليزية: The Great Masquerader)‏ هو مُصطلح طبي يُستخدم للدلالة على الحالات الطبية التي تتميز بأعراض غير مُحددة، وبالتالي يُمكن الخلط بينها وبين الحالات المرضية الأُخرى، ومُعظم هذه الحالات هي أمراض شاملة. من الأمراض التي تُوصف بهذا المُصطلح:
  • The Great Imitator (also the Great Masquerader) is a phrase used for medical conditions that feature nonspecific symptoms and may be confused with a number of other diseases. The term connotes especially difficult differential diagnosis (DDx), especial potential for misdiagnosis, and the protean nature of some diseases. Most great imitators are systemic in nature or have systemic sequelae, and an aspect of nonspecific symptoms is logically almost always involved. In some cases, an assumption that a particular sign or symptom, or a particular pattern of several thereof, is pathognomonic turns out to be false, as the reality is that it is only nearly so.
  • 偉大的模仿者(英語:The Great Imitator/The Great Masquerader,或譯為偉大的偽裝者)是形容部分無明顯症狀或特徵的疾病因不易診斷或辨別,進而造成醫療者將之與其他疾病混淆的情形。許多被稱為「偉大的模仿者」的疾病均是器官系統類型的疾病。下列的疾病因病徵不明顯,因此有時會被稱為「偉大的模仿者」: * 許多不同類型的癌症 * 許多風濕病症狀,其中包括: * 纖維肌痛 * 紅斑性狼瘡 * 系統性紅斑狼瘡 * 結節病 * 多發性硬化症 * 乳糜瀉 * 愛迪生氏病 * 肺栓塞 * 許多不同的感染性疾病,其中包括: * 梅毒 * 萊姆病 * * 結核病 * 布魯氏菌病 * 瘧疾
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