About: Vejocalcin

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Vejocalcin (VjCa, also called Vejocalcine) is a toxin from the venom of the Mexican scorpion Vaejovis mexicanus. Vejocalcin is a member of the of toxins. It acts as a cell-penetrating peptide (CPP); it binds with high affinity and specificity to skeletal ryanodine receptor 1 (RYR1) of the sarcoplasmic reticulum, thereby triggering calcium release from intracellular Ca2+ stores.

Attributes	Values
label	Vejocalcin
comment	Vejocalcin (VjCa, also called Vejocalcine) is a toxin from the venom of the Mexican scorpion Vaejovis mexicanus. Vejocalcin is a member of the of toxins. It acts as a cell-penetrating peptide (CPP); it binds with high affinity and specificity to skeletal ryanodine receptor 1 (RYR1) of the sarcoplasmic reticulum, thereby triggering calcium release from intracellular Ca2+ stores.
sameAs	Vejocalcin Vejocalcin Vejocalcin
name	Vejocalcin
topic	dbr:Inhibitor_cystine_knot dbr:Intrepicalcin wikipedia-en:Vejocalcin dbr:Vejocalcin#this
depiction
described by	proxy:entity/http/dbpedia.org/resource/Toxin https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/Template:Infobox https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/Pfam
Subject	Neurotoxins Ion channel toxins dbc:Scorpion_toxins
dbo:wikiPageID	61986499(xsd:integer)
dbo:wikiPageRevisionID	1093979534(xsd:integer)
dbo:wikiPageWikiLink	dbr:Knottin dbr:Vaejovis_mexicanus Cell-penetrating peptide Dissociation constant toxin dbr:Ryanodine dbr:Calcium-induced_calcium_release Cell membrane Post-translational modification UniProt Pfam Calcium channel dbr:PROSITE dbr:Channelopathies dbr:InterPro dbr:Vaejovis Neurotoxins Ion channel toxins dbr:Binding_affinity dbr:Inhibitor_cystine_knot dbr:Tertiary_structure dbr:RyR1 dbr:Intrepicalcin dbr:LD50 dbr:Molecular_dipole_moment dbr:Primary_sequence dbr:Sequence_similarity dbr:Sarcoplasmic_reticulum dbr:Calcins dbc:Scorpion_toxins dbr:Hemicalcin
dbo:wikiPageExternalLink	https://prosite.expasy.org/doc/PS60028/ http://pfam.xfam.org/family/PF08099/ https://www.uniprot.org/uniprot/P0DPT1/ https://www.ebi.ac.uk/interpro/entry/InterPro/IPR012632/ http://www.dsimb.inserm.fr/KNOTTIN/ https://www.uniprot.org/taxonomy/993612/ https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi%3Flvl=0&id=993612
is primary topic of	wikipedia-en:Vejocalcin
wasDerivedFrom	wikipedia-en:Vejocalcin?oldid=1093979534&ns=0
dbo:abstract	Vejocalcin (VjCa, also called Vejocalcine) is a toxin from the venom of the Mexican scorpion Vaejovis mexicanus. Vejocalcin is a member of the of toxins. It acts as a cell-penetrating peptide (CPP); it binds with high affinity and specificity to skeletal ryanodine receptor 1 (RYR1) of the sarcoplasmic reticulum, thereby triggering calcium release from intracellular Ca2+ stores.
dbo:thumbnail	wiki-commons:Special:FilePath/Vejocalcin.jpg?width=300
dbp:caption	3(xsd:integer)
dbp:data	993612(xsd:integer) https://prosite.expasy.org/doc/PS60028/ http://pfam.xfam.org/family/PF08099/ dbr:Knottin dbr:Vaejovis_mexicanus https://www.uniprot.org/uniprot/P0DPT1/ https://www.ebi.ac.uk/interpro/entry/InterPro/IPR012632/ dbr:Vaejovis Scorpion Calcin Family Vejocalcin VjCa
dbp:header	Identifiers Family and Domains Names and Taxonomy
dbp:headerstyle	background:#F6E7B0;
dbp:label	UniProt Pfam dbr:PROSITE dbr:InterPro Organism Domain Short name Recommended name Sequence Similarities Taxonomic Identifier Taxonomic Lineage
dbp:title	Vejocalcin
dbo:wikiPageLength	12193(xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Reflist dbt:Infobox dbt:Short_description dbt:Square_bracket_close dbt:Square_bracket_open
is sameAs of	Vejocalcin
is topic of	toxin Pfam dbt:Infobox

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